How does coronavirus kill?

[frnash]

How does coronavirus kill?

The following article, from a well-regarded publication, that attempts to explain what it s about the novel corona virus (COVID-19) that has wreaked so much havoc over the last 4-5 months. While there are some technical terms that are pretty sophisticated within the article, for those of you who ask questions like "is really just like having the flu" to "does the body's reaction to the virus cause many of side-effects that the flu alone causes", the following paper was remarkably well-written and accessible.

While preliminary, here for your consideration is the best summary of how, why and where the corona virus attacks and damages the body:

From Science magazine Apr. 17, 2020 …
(click →) How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes.

 

[slimcake]

There should also be a counter story about all the thousands of people who show ZERO symptoms. That this virus has absolutely no effect on them. Only read the first bit but it sure sounded like the worst case and doom and gloom. I told myself I would avoid fear mongering and negative news.

 

[frnash]

There should also be a counter story about all the thousands of people who show ZERO symptoms. That this virus has absolutely no effect on them. Only read the first bit but it sure sounded like the worst case and doom and gloom. I told myself I would avoid fear mongering and negative news.

That article includes much discussion of asymptomatic cases.

 

[rp7x]

A gun shot may not kill you , feel lucky ?

 

[slimcake]

A gun shot may not kill you , feel lucky ?

At least I could see the gun... I don't know how that comparison works here

 

[G]

The coronavirus kills by pneumonia. Next question.

 

[G]

When this is over they will go back and realize that the the first response was in error. Instead of sending people home to isolate they should have admitted them to empty hospitals and put nasal canulas in every one of them.

 

[Tracker]

The coronavirus kills by pneumonia. Next question.

Does that mean that pneumonia kills by coronavirus?

 

[frnash]

The coronavirus kills by pneumonia. Next question.

And so very many other ways, as discussed in the article. I guess you didn't read it.

Sorry if it's being written at above a third grade reading level was a problem.

 

[Tracker]

FRNASH....you do realize that coronavirus hits every year in a slightly different configuration...but its nothing new....just like last year and the year before that and that....and all of them would kill you if you got a bad case of untreated pneumonia.....just sayin'

 

[frnash]

FRNASH....you do realize that coronavirus hits every year in a slightly different configuration...but its nothing new....just like last year and the year before that and that....and all of them would kill you if you got a bad case of untreated pneumonia.....just sayin'

Pneumonia, respiratory failure, yes, perhaps to be expected, but they are realizing that although the lungs are ground zero, its reach can extend to many organs including the heart and blood vessels, kidneys, gut, and brain.

The heart:

… heart attack, including telltale signs in the electrocardiogram and high levels of a blood marker suggesting damaged cardiac muscles. Further tests showed cardiac swelling and scarring, and a left ventricle — normally the powerhouse chamber of the heart — so weak that it could only pump one-third its normal amount of blood. But when doctors injected dye in the coronary arteries, looking for the blockage that signifies a heart attack, they found none.
​

… blood that clots abnormally.

… blood vessel constriction. Reports are emerging of ischemia in the fingers and toes — a reduction in blood flow that can lead to swollen, painful digits and tissue death, amputation.

… renal (kidney) failure.

… injury to the liver or bile ducts.

… digestive system impact, colon injury.

… brain inflammation: meningitis and encephalitis, seizures, strokes — suggesting it can penetrate the central nervous system.

… conjunctivitis — pink, watery eyes.

---

Enuf fer ya?
This ain't yer granddaddy's "flu virus" (or a variant thereof)!

 

[G]

Hypoxia. It does not matter which organ fails second. Pick one. The problem originates in the lungs. It is a flue virus. Nothing more nothing less. Whether it is you or your granddaddy it doesn't care. It will kill you if you are old or weak or have an underlying health issue or three. If you are like 99 % of the rest of the population there is simply not much to worry about. But hey don't listen to me. Wait six months when this fiasco has played out and you aren't dead. Your finances will be dead but you will be alive and well and wonder how this could have happened to somebody as smart as you.

 

[Tracker]

FRNASH...it has been around for eons....its the same darn flu that has happened over and over again...even 1918 was coronavirus....you are being hoodwinked by the corrupt democrats....heres from coronavirus evolution...and I quote...read it


The most recent common ancestor (MRCA) of all coronaviruses is estimated to have existed as recently as 8000 BCE, although some models place the common ancestor as far back as 55 million years or more, implying long term coevolution with bat and avian species.[37] The most recent common ancestor of the alphacoronavirus line has been placed at about 2400 BCE, the betacoronavirus line at 3300 BCE, the gammacoronavirus line at 2800 BCE, and the deltacoronavirus line at about 3000 BCE. Bats and birds, as warm-blooded flying vertebrates, are an ideal natural reservoir for the coronavirus gene pool (bats the reservoir for alphacoronavirus and betacoronavirus – and birds the reservoir for gammacoronavirus and deltacoronavirus). The large number of host bat and avian species, and their global range, has enabled extensive evolution and dissemination of coronaviruses.[38]

Many human coronavirus have their origin in bats.[39] The human coronavirus NL63 shared a common ancestor with a bat coronavirus (ARCoV.2) between 1190–1449 CE.[40] The human coronavirus 229E shared a common ancestor with bat coronavirus (GhanaGrp1 Bt CoV) between 1686–1800 CE.[41] More recently, alpaca coronavirus and human coronavirus 229E diverged sometime before 1960.[42] MERS-CoV emerged in humans from bats through the intermediate host of camels.[43] MERS-CoV, although related to several bat coronavirus species, appears to have diverged from these several centuries ago.[44] The most closely related bat coronavirus and SARS-CoV diverged in 1986.[45] A possible path of evolution, of SARS coronavirus and keen bat coronaviruses, suggests that SARS related coronaviruses coevolved in bats for a long time. The ancestors of SARS-CoV first infected leaf-nose bats of the genus Hipposideridae; subsequently, they spread to horseshoe bats in the species Rhinolophidae, and then to civets, and finally to humans.[46][47]

Unlike other betacoronaviruses, bovine coronavirus of the species Betacoronavirus 1 and subgenus Embecovirus is thought to have originated in rodents and not in bats.[39][48] In the 1790s, equine coronavirus diverged from the bovine coronavirus after a cross-species jump.[49] Later in the 1890s, human coronavirus OC43 diverged from bovine coronavirus after another cross-species spillover event.[50][49] It is speculated that the flu pandemic of 1890 may have been caused by this spillover event, and not by the influenza virus, because of the related timing, neurological symptoms, and unknown causative agent of the pandemic.[51] Human coronavirus OC43 besides causing respiratory infections is also suspected of playing a role in neurological diseases.[52] In the 1950s, the human coronavirus OC43 began to diverge into its present genotypes.[53] Phylogentically, mouse hepatitis virus (Murine coronavirus), which infects the mouse's liver and the central nervous system,[54] is related to human coronavirus OC43 and bovine coronavirus. Human coronavirus HKU1, like the aforementioned viruses, also has its origins in rodents.

 

[G]

Go get yourself a pulse oximeter. $50 bucks or less at just about any pharmacy. If you are perfusing at less than about 95% you have something going on. My own perfusion rate is 98 and has been for years. Way better quick check of health than a temp reading. If your O levels go down all organs are effected. It all starts with O. Think about it. The second you are born all they want to do is get you to breathe. They don't care about pancreatic function or colon health. It all starts with O.

 

[Tracker]

More....it ain't new at all....again...BS by democrats


Coronaviruses were first discovered in the 1930s when an acute respiratory infection of domesticated chickens was shown to be caused by infectious bronchitis virus (IBV).[9] Arthur Schalk and MC Hawn described in 1931 a new respiratory infection of chickens in North Dakota

 

[G]

Also if you spend the $50 bucks or less on a pulse oximeter you get - surprise - the pulse function. This is kind of fun too. If your pulse is under 50 and you are not an Olympic triathlon person you should probably seek a medical professional. On the other side if your pulse is over 150 you should probably slow down on the methamphetamine or at least take some 'ludes to balance out a little. $50 bucks well spent. Don't leave home without it.

 

[frnash]

Hypoxia. It does not matter which organ fails second. Pick one. The problem originates in the lungs. …

Except when it (frequently) originates elsewhere, as when the COVID-19 (a.k.a. SARS-CoV-2) virus latches on to the cell-surface receptors called angiotensin-converting enzyme 2 (ACE2), which are found throughout the body.

It is a flue [sic] virus. …

It is? Well in that case whatcha gots ta do is hire a chimney sweep to scrape all that nasty soot-virus outa yer flue!

Go get yourself a pulse oximeter. $50 bucks or less at just about any pharmacy. If you are perfusing at less than about 95% you have something going on. My own perfusion rate is 98 and has been for years. …

One of those little gizmos can't 'splain how some patients with extremely low blood-oxygen levels are not gasping for breath, but it's prob'ly a nice toy.

---

FRNASH...it has been around for eons....its the same darn flu that has happened over and over again...even 1918 was coronavirus....you are being hoodwinked by the corrupt democrats....heres from coronavirus evolution...and I quote...read it
…
The most recent common ancestor (MRCA) of all coronaviruses is estimated to have existed as recently as 8000 BCE, although some models place the common ancestor as far back as 55 million years or more, implying long term coevolution with bat and avian species.[37] …

More....it ain't new at all....again...BS by democrats
…
Coronaviruses were first discovered in the 1930s when an acute respiratory infection of domesticated chickens was shown to be caused by infectious bronchitis virus (IBV).[9] …

Well lookie there, the Great and Wonderful Wizard of Oz… er, Yoda… er, Jedi Master… er, Tracker casts asparagus at that evil demon-crat political screed — Science Magazine as he quoteth (without attribution) from that oh so reliable font of irrefutable wisdom — Wickedypedia!

'Magine that! My hed is gonna 'splode!

 

[G]

Believe what you want to believe. The odds are very good you will still be believing what you want to believe 6 months from now and a year from now. You might tip from something else but not this bug.

 

[euphoric1]

Pneumonia, respiratory failure, yes, perhaps to be expected, but they are realizing that although the lungs are ground zero, its reach can extend to many organs including the heart and blood vessels, kidneys, gut, and brain.

The heart:

… heart attack, including telltale signs in the electrocardiogram and high levels of a blood marker suggesting damaged cardiac muscles. Further tests showed cardiac swelling and scarring, and a left ventricle — normally the powerhouse chamber of the heart — so weak that it could only pump one-third its normal amount of blood. But when doctors injected dye in the coronary arteries, looking for the blockage that signifies a heart attack, they found none.
​

… blood that clots abnormally.

… blood vessel constriction. Reports are emerging of ischemia in the fingers and toes — a reduction in blood flow that can lead to swollen, painful digits and tissue death, amputation.

… renal (kidney) failure.

… injury to the liver or bile ducts.

… digestive system impact, colon injury.

… brain inflammation: meningitis and encephalitis, seizures, strokes — suggesting it can penetrate the central nervous system.

… conjunctivitis — pink, watery eyes.

---

Enuf fer ya?
This ain't yer granddaddy's "flu virus" (or a variant thereof)!

And it isn't going away any time soon...time for the country to go back to work.

 

[dfattack]

And it isn't going away any time soon...time for the country to go back to work.

That's what gets me the most. Those that say this is so deadly or contagious...yes, we agree however we can't eradicate it within the next few weeks and cannot stay at home much longer. Just because this is a deadly virus doesn't mean we can stay home and not re-open the economy until it's completely gone. Not going to happen. Herd immunity is the only way. Vaccine is another option but that's a long way out...unless china has it and isn't sharing.

I'm also slowly getting to the point where I don't think masks or social distancing are going to make any difference. Those that promoted it probably won't ever admit it but some will. In fact they already are. Watch Life Liberty and Levin re-play of last Sunday night's episode.

I'm hearing the two largest cities in China have no cases. Not sure what we can believe but if true...makes you think a little...